Overview
Posaconazole (CAS 171228-49-2 ), also referenced in development literature as SCH 56592, is a broad-spectrum triazole antifungal active pharmaceutical ingredient marketed under the brand name Noxafil.
It targets invasive fungal infections caused by Aspergillus and Candida species, positioning it as a critical API in antifungal therapy manufacturing for global pharmaceutical supply chains.
Posaconazole is formulated into oral suspensions, delayed-release tablets, and intravenous solutions for prophylaxis and treatment of invasive fungal infections in immunocompromised patients.
Pharmaceutical manufacturers source it as an API for finished dosage form production under GMP conditions. In biotechnology, it is used as a reference standard for antifungal susceptibility testing.
Contract development organizations also use this compound in formulation development work targeting improved bioavailability delivery systems and advanced drug interaction studies in clinical research.
The product is supplied as a white to off-white crystalline powder. It is available in research-grade and GMP-compliant pharmaceutical-grade specifications to meet the requirements of regulated drug manufacturing.
Our material meets rigorous quality standards including USP and EP requirements. Quantities range from small research lots through commercial-scale API batches for industrial use.
Documentation packages including CoA, impurity profiles, and regulatory support files are available upon request to ensure full compliance with international pharmaceutical manufacturing protocols.
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Physical Properties
| Melting Point | 171.00 °C |
| Boiling Point | 850.7±75.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Flash Point | 9°C |
| Appearance | White Solid |
| Color | white to beige |
| Form | powder |
Safety & Handling
Danger GHS07 GHS08 GHS09 Hazard Statements H319 Causes serious eye irritation H351 Suspected of causing cancer H361 Suspected of damaging fertility or the unborn child H372 Causes damage to organs through prolonged or repeated exposure H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P318 IF exposed or concerned, get medical advice. P319 Get medical advice/attention if you feel unwell. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 3204.90.0000 |
| UN Number | 1230 |
| Packing Group | II |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 171228-49-2
- EC Number
- 682-747-8
- Mol. Weight
- 700.8
- HS Code
- 3204.90.0000
- Category
- Heterocyclic Compounds