2-Adamantanamine hydrochloride

2-Adamantanamine hydrochloride (CAS 10523-68-9 ), also known as 2-Aminoadamantane hydrochloride, is a bridged-ring amine salt used as a building block in pharmaceutical synthesis.

Its rigid adamantane scaffold is valued in drug design for improving metabolic stability and receptor selectivity in candidate molecules. The compound serves as a key intermediate in the synthesis of CNS-active pharmaceuticals.

The adamantane core is incorporated to enhance binding affinity at specific neurological targets. In antiviral and antidiabetic drug development, adamantane-derived amines are used to construct scaffolds for DPP-4 inhibitors.

These amines also function as ion channel modulators. Medicinal chemistry programs use this compound in SAR studies to evaluate the effect of the bridged ring system on pharmacokinetic profiles.

Biotech research applications include its use as a coupling partner in the preparation of labeled probes. These are frequently utilized in conjugates for receptor binding assays during drug discovery phases.

2-Adamantanamine hydrochloride is supplied as a white crystalline powder. It is available in research quantities through to multi-kilogram lots to support both early-stage discovery and process development.

Material is typically offered to pharmaceutical-grade specifications. Documentation includes CoA, HPLC purity data, and residual solvent profiles aligned with ICH guidelines to ensure high quality standards.

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