Overview
Diethylamine hydrochloride (CAS 660-68-4 ), also referred to as Diethylamine HCl, is the stable salt form of diethylamine produced by neutralization with hydrochloric acid.
It functions primarily as a chemical intermediate and preservation agent across pharmaceutical, personal care, and water treatment applications. In pharmaceutical manufacturing, it serves as a key intermediate.
This compound is used in the synthesis of active ingredients, particularly where a controlled, non-volatile amine source is required. Personal care formulators incorporate it into preservation systems.
It is used in pH-adjusted formulations where amine reactivity must be moderated for product stability. Water treatment programs use it as a biocide precursor and process chemical to control microbial growth.
Its role as a stable amine salt also makes it suitable for use in buffer preparation and analytical reagent applications. Diethylamine hydrochloride is supplied as a white crystalline powder.
It is available in technical and pharmaceutical grades, with pharmaceutical-grade material typically meeting USP or Ph. Eur. specifications for industrial use.
Packaging is offered in standard drum and bulk quantities to support both laboratory-scale and industrial procurement requirements. This ensures consistent supply for various manufacturing needs.
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Physical Properties
| Melting Point | 228.5 °C |
| Boiling Point | 330 °C |
| Density | 1.0 g/mL at 20 °C |
| Flash Point | 320-330°C |
| Appearance | white to off-white crystals or crystalline powder |
| Color | White to off-white |
| Form | Liquid |
| Water Solubility | soluble |
| Vapor Pressure | <0.00001 hPa (20 °C) |
| Refractive Index | 1.5320 (estimate) |
| pH | 4.5-6.5 (10g/l, H2O, 20℃) |
| Log P | -1.3 at 20℃ |
Safety & Handling
Danger GHS05 GHS07 Hazard Statements H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29211200 |
| UN Number | 1993 |
| ADR Class | 3 |
| Packing Group | III |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 660-68-4
- EC Number
- 211-541-9
- Mol. Weight
- 109.60
- HS Code
- 29211200
- Category
- Amines