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Monomers & Building Blocks

3-(2-methoxy-5-methylphenyl)-3-phenylpropanoic acid

CAS: 109089-77-2

Overview

3-(2-Methoxy-5-methylphenyl)-3-phenylpropanoic acid (CAS 109089-77-2 ) is a specialty organic acid used as a pharmaceutical intermediate and synthetic building block. Its diaryl-substituted propanoic acid structure makes it a targeted precursor.

This chemical is essential in the construction of complex active pharmaceutical ingredient (API) frameworks. In pharmaceutical synthesis, it serves as a key intermediate for assembling molecules requiring a defined diarylmethine carbon center.

It supports medicinal chemistry programs and API development pipelines. Formulation researchers and contract manufacturers source it for small-scale synthesis routes where precise stereochemical control at the benzylic position is commercially relevant.

In biotechnology and life sciences research, it supports the preparation of probe compounds and reference standards used in assay development. Its carboxylic acid functionality also positions it as a monomer candidate.

This material is often utilized in specialty polymer research requiring aromatic acid building blocks. This compound is supplied primarily as a solid powder suited for laboratory and pilot-scale procurement for industrial use.

It is available in research and custom synthesis quantities, typically at high purity grades appropriate for pharmaceutical intermediate use. Buyers should confirm lot-specific analytical data, including HPLC purity and NMR characterization.

When sourcing for regulated synthesis workflows, ensuring the material meets internal quality benchmarks is critical. This specialty chemical remains a versatile tool for advanced organic synthesis and chemical manufacturing applications.

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Physical Properties

Melting Point134-136 °C
AppearanceWhite Crystalline Solid

Safety & Handling

Warning GHS07 Hazard Statements H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. P321 Specific treatment (see … on this label). P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other Names

RefChem:491117 | 3-(2-methoxy-5-methylphenyl)-3-phenylpropionic acid | Benzenepropanoic acid2-methoxy-5-methyl-β-phenyl- | Hydrocinnamic acid2-methoxy-5-methyl-β-phenyl- | 2-Methoxy-5-methyl-β-phenylbenzenepropanoic acid

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Chemical Properties

CAS Number
109089-77-2
EC Number
600-896-9
Mol. Weight
270.32

Industries

Documentation