Overview
Thiophene (CAS 110-02-1 ), also known as thiofuran or thiole, is a sulfur-containing heterocyclic compound used as a chemical intermediate and flavoring agent in the food and fragrance industry.
It provides a characteristic sulfurous, meat-like aromatic profile that underpins a range of synthetic flavor systems. In food flavoring, thiophene derivatives are used to recreate roasted, cooked meat, and savory notes.
These compounds are essential in processed food products, seasonings, and flavor blends. It also functions as a key building block in the synthesis of more complex heterocyclic flavor compounds for the industry.
The ring structure is modified to produce targeted aroma profiles for various applications. Fragrance formulators use thiophene-based intermediates in specialty compositions requiring sulfurous or roasted character.
Beyond flavor and fragrance, it serves as a synthetic intermediate in fine chemical and pharmaceutical manufacturing. The thiophene ring is frequently incorporated into active compound structures for medicine.
Thiophene is supplied as a liquid in standard commercial packaging, with drum and bulk quantities available for industrial buyers. It is offered in technical and high-purity grades for diverse needs.
Purity levels are typically at 99% or above for flavor and fine chemical applications. Buyers should confirm grade specifications against their formulation or synthesis requirements prior to sourcing materials.
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Physical Properties
| Melting Point | -39.4 °C |
| Boiling Point | 84.0 °C @ Press: 760 Torr |
| Density | 1.06494 g/cm³ @ Temp: 20 °C |
| Flash Point | -9 °C |
| Appearance | colourless to pale yellow liquid |
| Color | Clear |
| Odor | at 0.10 % in propylene glycol. alliaceous garlic |
| Form | powder |
| Water Solubility | INSOLUBLE |
| Vapor Pressure | 40 mm Hg ( 12.5 °C) |
| Refractive Index | n 20/D 1.529(lit.) |
| Log P | 1.81-1.86 at pH10 |
Safety & Handling
Danger GHS02 GHS05 GHS06 GHS07 GHS08 Hazard Statements H225 H225 H302 H302 H312 H312 H315 H315 H318 H318 H319 H319 H331 H331 H332 H332 H335 H335 H373 H373 H402 H402 H412 H412 Precautionary Statements P210 P210 P233 P233 P240 P240 P241 P241 P242 P242 P243 P243 P260 P260 P261 P261 P264 P264 P270 P270 P271 P271 P273 P273 P280 P280 P316 P316 P317 P317 P319 P319 P321 P321 P330 P330 P405 P405 P501 P501 P264+P265 P264+P265 P301+P317 P301+P317 P302+P352 P302+P352 P304+P340 P304+P340 P332+P317 P332+P317 P337+P317 P337+P317 P362+P364 P362+P364 P370+P378 P370+P378 P403+P233 P403+P233 P403+P235 P403+P235 P303+P361+P353 P303+P361+P353 P305+P351+P338 P305+P351+P338 P305+P354+P338 P305+P354+P338
Trade & Regulatory
| HS Code | 29349990 |
| UN Number | 2414 |
| ADR Class | 3 |
| Packing Group | II |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 110-02-1
- EC Number
- 203-729-4
- Mol. Weight
- 84.14
- HS Code
- 29349990
- Category
- Flavors & Fragrances