Overview
Arginine hydrochloride (CAS 1119-34-2 ), also known as L-Arginine HCL, is the hydrochloride salt form of the amino acid arginine, offering greater solubility and stability than the free base.
Under the brand name R-Gene 10, it has established clinical use as an intravenous diagnostic agent. Across industries, it functions as a pH buffer, humectant, and stabilizing agent in various formulations.
In injectable and oral pharmaceutical formulations, it stabilizes proteins and peptides while buffering pH in sensitive drug products. Nutritional supplement manufacturers use it to produce high-concentration powders.
It is frequently used in tablets and functional beverages where solubility is a critical processing requirement. In personal care, it conditions and moisturizes skin and hair formulations effectively.
This is particularly true in rinse-off and leave-on products targeting hydration. Food and clinical nutrition producers incorporate it into medical foods and enteral nutrition products for precise delivery.
Arginine hydrochloride is supplied as a white crystalline powder. It is available in USP , BP , and Ph. Eur. grades for pharmaceutical and clinical applications.
It is also available in food-grade specifications compliant with FCC standards. Bulk quantities are standard for industrial buyers, with smaller quantities available for R&D and quality testing.
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Physical Properties
| Melting Point | 215 °C |
| Boiling Point | 235°C[at 101 325 Pa] |
| Density | 1.42 |
| Appearance | White crystalline powder |
| Color | white |
| Odor | odorless |
| Form | powder |
| Water Solubility | Soluble in water. Slightly soluble in hot alcohol. |
| Vapor Pressure | <1 Pa (20 °C) |
| pH | 5.5-7.0 (25℃, 1M in H2O) |
| Log P | -8.5--3.24 at 25℃ |
Safety & Handling
Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation Precautionary Statements P264 Wash … thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P321 Specific treatment (see … on this label). P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29252000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Other Names
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Chemical Properties
- CAS Number
- 1119-34-2
- EC Number
- 214-275-1
- Mol. Weight
- 210.66
- HS Code
- 29252000
- Category
- Salts & Minerals