Metronidazole

Metronidazole (CAS 443-48-1 ) is an antiprotozoal and antibacterial active pharmaceutical ingredient used across human and veterinary medicine. It targets anaerobic bacteria and protozoa, making it a core API in prescription drug manufacturing globally.

In pharmaceutical manufacturing, this active is formulated into oral tablets, suspensions, and intravenous solutions for treating infections caused by anaerobic organisms. These include bacterial vaginosis, trichomoniasis, and Clostridioides difficile.

Topical formulations such as gels and creams are produced for dermatological indications, including rosacea management. Here, the active is incorporated at defined concentrations into semi-solid bases for targeted delivery.

Veterinary drug manufacturers use the compound in oral and injectable preparations targeting gastrointestinal anaerobic infections. These applications are common in both companion animals and livestock health management.

In cosmetic and personal care formulations, it appears in select anti-redness and skin-calming products. This occurs where regulatory frameworks permit its use as an active ingredient for specific skin conditions.

The material is supplied as a white to off-white crystalline powder. It is available in USP , BP , and Ph. Eur. pharmacopoeial grades to meet the documentation requirements of regulated pharmaceutical markets.

API-grade material is the standard commercial form for industrial use. Micronized particle size variants are also available to support specific formulation requirements and ensure optimal bioavailability in finished products.

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