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Heterocyclic Compounds

Methimazole

CAS: 60-56-0

Overview

Methimazole (CAS 60-56-0 ), also known by the trade name Tapazole and abbreviated as MMI, is an active pharmaceutical ingredient and synthesis intermediate used across pharmaceutical manufacturing and select industrial processes.

It functions as a thyroid hormone synthesis inhibitor in drug formulations and as a stabilizing agent in industrial chemical applications. In pharmaceutical manufacturing, MMI is the active substance in antithyroid drug products.

This makes it a direct procurement target for API suppliers and finished-dose formulators. Textile and leather processors source it as a corrosion inhibitor and stabilizing additive in processing baths where metal ion control is critical.

In paper manufacturing, it is applied as a biocide and preservation agent to extend the service life of process fluids. MMI also serves as a building block in heterocyclic synthesis for chemical production.

Its reactive thione group supports the production of more complex pharmaceutical intermediates. Methimazole is supplied as a white crystalline powder in bulk quantities suited to both pharmaceutical and industrial procurement.

Pharmaceutical-grade material is available to USP and BP specifications, supporting API and formulation manufacturing requirements. Technical-grade material is available for industrial applications.

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Physical Properties

Melting Point146-148 °C
Boiling Point280 °C
Density1.35 g/cm³
Flash Point280°C
AppearanceWhite Solid
ColorWhite to slightly cream or pale buff
FormCrystalline Powder
Water Solubilitysoluble
Refractive Index1.5000 (estimate)

Safety & Handling

Warning GHS07 GHS08 Hazard Statements H302 H302 H317 H317 H361 H361 Precautionary Statements P203 P203 P261 P261 P264 P264 P270 P270 P272 P272 P280 P280 P318 P318 P321 P321 P330 P330 P405 P405 P501 P501 P301+P317 P301+P317 P302+P352 P302+P352 P333+P317 P333+P317 P362+P364 P362+P364

Trade & Regulatory

HS Code29332990
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

1-methylimidazole-2(3H)-thione | 1-methyl-13-dihydro-2H-imidazole-2-thione | Tapazole | 1-Methyl-1H-imidazole-2-thiol | 1-Methylimidazole-2-thiol | Mercazole | Thiamazol | 2H-Imidazole-2-thione13-dihydro-1-methyl- | MMI

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Chemical Properties

CAS Number
60-56-0
EC Number
200-482-4
Mol. Weight
114.17
HS Code
29332990

Industries

Documentation