Overview
Triethylamine hydrochloride (CAS 554-68-7 ), also known as triethylammonium chloride and commonly abbreviated as TEA·HCl, is the stable salt form of triethylamine produced by neutralization with hydrochloric acid.
It functions primarily as a pH buffer, reaction intermediate, and auxiliary agent across pharmaceutical synthesis, textile processing, and specialty chemical manufacturing for various industrial applications.
In pharmaceutical manufacturing, TEA·HCl acts as a buffering agent and counterion source in API synthesis, where controlled pH and stable amine delivery are critical to reaction yield and purity.
Textile and leather processors use it as an auxiliary in dyebath formulations, improving dye uptake and fixation on fiber substrates. In paper treatment, it supports surface chemistry modifications.
This occurs where controlled charge interaction between fiber and coating agents is required. It also serves as a synthetic intermediate in the preparation of quaternary ammonium compounds.
These compounds and other specialty amines are used in preservation and biocide formulations. Triethylamine hydrochloride is supplied as a white crystalline powder or granular solid for easy handling.
Standard commercial grades include technical and pharmaceutical-grade material, with pharmaceutical supply typically conforming to in-house or compendial specifications depending on the intended synthesis application.
Packaging ranges from small laboratory quantities to bulk industrial supply. This ensures that the material meets the rigorous demands of both research facilities and large-scale chemical production plants.
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Physical Properties
| Melting Point | 260 °C (decomp) |
| Boiling Point | <245 °C |
| Density | 1.0689 g/cm³ @ Temp: 21 °C |
| Appearance | White to off-white crystalline powder |
| Color | White to off-white |
| Form | Crystalline Powder |
| Water Solubility | 1440 g/L (20 ºC) |
| Refractive Index | 1.4530 (estimate) |
| pH | 5 (10g/l, H2O, 20℃) |
Safety & Handling
Danger GHS05 GHS07 Hazard Statements H314 Causes severe skin burns and eye damage H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P316 Get emergency medical help immediately. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P363 Wash contaminated clothing before reuse. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P301+P330+P331 Rinse mouth. Do NOT induce vomiting. P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29211910 |
| WGK (Germany) | 1 |
Other Names
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Chemical Properties
- CAS Number
- 554-68-7
- EC Number
- 209-067-2
- Mol. Weight
- 137.65
- HS Code
- 29211910
- Category
- Pigments & Colorants