Overview
Chlorhexidine acetate (CAS 56-95-1 ), also known as chlorhexidine diacetate and sold under the trade name Hibitane diacetate, is a broad-spectrum antimicrobial salt used across pharmaceutical, personal care, and healthcare manufacturing.
It delivers reliable bactericidal and fungicidal activity at low concentrations, making it a preferred active ingredient where microbial control is a critical formulation requirement for industrial and medical applications.
In pharmaceutical manufacturing, it is incorporated into topical antiseptic solutions, wound care products, and surgical scrubs where regulatory-grade antimicrobial performance is required for safety and efficacy.
Personal care formulators use it as a preservative and active biocide in mouthwashes, skin cleansers, and intimate hygiene products. Water treatment applications include its use as a biocide for controlling microbial growth.
It also functions as a preservative in ophthalmic preparations and contact lens solutions, where low irritation potential at effective concentrations is a key formulation consideration for manufacturers.
Chlorhexidine acetate is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications including BP and Ph. Eur. , which are the standard grades demanded.
These quality standards ensure the material is suitable for healthcare and regulated personal care markets. Technical-grade material is also available for industrial biocide applications and process water treatment.
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Physical Properties
| Melting Point | 154-155 °C |
| Appearance | White or almost white, microcrystalline powder |
| Color | White to Almost white |
| Form | neat |
| Water Solubility | 1.9 g/100 mL (20 ºC) |
| Log P | 4.931 (est) |
Safety & Handling
Danger GHS06 GHS07 GHS09 GHS05 GHS08 Hazard Statements H301 Toxic if swallowed H302 Harmful if swallowed H317 May cause an allergic skin reaction H318 Causes serious eye damage H319 Causes serious eye irritation H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects H411 Toxic to aquatic life with long lasting effects Precautionary Statements P233 Keep container tightly closed. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P284 In case of inadequate ventilation wear respiratory protection. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P403 Store in a well-ventilated place. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P316 Get emergency medical help immediately. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P342+P316 Get emergency medical help immediately. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 2925294500 |
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 56-95-1
- EC Number
- 200-302-4
- Mol. Weight
- 625.5
- HS Code
- 2925294500
- Category
- Salts & Minerals