Overview
Triphenylphosphine (CAS 603-35-0 ), commonly abbreviated as TPP, is a phosphorus-based ligand and reagent used across pharmaceutical synthesis, polymer stabilization, and specialty chemical manufacturing.
It functions primarily as a catalyst component, reducing agent, and stabilizer precursor in demanding industrial processes. In pharmaceutical manufacturing, TPP is a key reagent in Mitsunobu and Wittig reactions.
This material enables stereoselective synthesis of active pharmaceutical ingredients at scale. Polymer producers incorporate it as a processing stabilizer and catalyst precursor in polyester and polyurethane systems.
In these applications, it controls oxidative degradation during high-temperature compounding. Printing ink and packaging formulators use TPP-derived systems as photoinitiator components and stabilizers.
These additives extend the service life of UV-curable coatings. In specialty catalyst systems, it acts as a ligand for palladium, rhodium, and other transition metals, supporting cross-coupling reactions.
Such reactions are critical to fine chemical production. Triphenylphosphine is supplied as a white crystalline powder and is available in technical grade for industrial catalyst and polymer applications.
It is also offered in high-purity grades meeting pharmaceutical manufacturing requirements. Packaging options typically range from kilogram-scale bags to bulk drum quantities to suit various needs.
These formats support both R&D and production-scale procurement. Our logistics network ensures reliable delivery of this essential phosphorus-based reagent for your specific industrial requirements.
Contact us for supply of Triphenylphosphine
Physical Properties
| Melting Point | 80.5 °C |
| Boiling Point | >360 °C |
| Density | 1.075 g/cm³ @ Temp: 80 °C |
| Flash Point | 181 °C |
| Appearance | White, crystalline solid. Insoluble inwater; slightly soluble in alcohol; soluble in benzene, acetone, carbon tetrachloride. Combustible. |
| Color | White |
| Odor | odorless |
| Form | Crystals, Crystalline Powder or Flakes |
| Water Solubility | Insoluble |
| Vapor Pressure | 5 mm Hg ( 20 °C) |
| Refractive Index | 1.6358 |
Safety & Handling
Danger GHS05 GHS07 GHS08 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation H350 May cause cancer H372 Causes damage to organs through prolonged or repeated exposure H373 May causes damage to organs through prolonged or repeated exposure H412 Harmful to aquatic life with long lasting effects H413 May cause long lasting harmful effects to aquatic life Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29310095 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 2 |
Other Names
Related Products
Chemical Properties
- CAS Number
- 603-35-0
- EC Number
- 210-036-0
- Mol. Weight
- 262.3
- HS Code
- 29310095
- Category
- Flavors & Fragrances