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Amino Acids & Peptides

Ethyl lauroyl arginate hydrochloride

CAS: 60372-77-2

Overview

Ethyl lauroyl arginate hydrochloride (CAS 60372-77-2 ), commercially known as LAE or Cytoguard LA and approved as E243 in the EU, is a cationic antimicrobial derived from natural amino acid and fatty acid precursors.

It functions as a broad-spectrum preservative and surface-active biocide across food, personal care, and pharmaceutical applications. In food manufacturing, E243 is approved for use in processed meats and certain bakery products.

This ingredient inhibits bacterial and yeast growth, extending shelf life without synthetic preservative blends. Personal care formulators incorporate LAE into rinse-off and leave-on products including shampoos and conditioners.

In these applications, it delivers both antimicrobial preservation and conditioning activity on hair and skin surfaces. In pharmaceutical topical formulations, it functions as a preservative system component where low-toxicity actives are preferred.

Home care and surface disinfection products use LAE for its rapid bactericidal action against Gram-positive and Gram-negative organisms. It remains effective at low use concentrations across various industrial formulations.

Ethyl lauroyl arginate hydrochloride is supplied as a white to off-white powder or as aqueous solution concentrates. Food-grade material is available meeting E243 regulatory specifications for global distribution.

Cosmetic-grade supply aligns with INCI-compliant quality standards for international beauty brands. Technical and pharmaceutical grades are also available depending on specific end-use requirements and purity needs.

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Physical Properties

Density1.11[at 20°C]
ColorWhite
FormSolid
Water Solubility247g/L@20°C
Vapor Pressure0.001Pa@25°C
Log P1.43 at 20℃

Safety & Handling

Danger GHS05 GHS09 GHS07 Hazard Statements H315 Causes skin irritation H318 Causes serious eye damage H400 Very toxic to aquatic life H412 Harmful to aquatic life with long lasting effects Precautionary Statements P264 Wash … thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P391 Collect spillage. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2925299000
UN Number3077
ADR Class9
Packing GroupIII
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

Ethyl lauroyl arginate HCl | Cytoguard LA | XPD6ZY79TB | AMINAT G | L-ArginineN2-(1-oxododecyl)-ethyl estermonohydrochloride | E-243 | RefChem:596249 | ETHYL-NALPHA-LAUROYL-L-ARGINATE HYDROCHLORIDE | LAE | E243

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Chemical Properties

CAS Number
60372-77-2
EC Number
434-630-6
Mol. Weight
421.0
HS Code
2925299000

Industries

Documentation