Overview
Sodium malate (CAS 676-46-0 ), also known by its food additive designation E350i , is the disodium salt of malic acid used commercially as a pH buffer and acidulant.
It delivers a mild, smooth tartness without the sharp acidity of mineral acids, making it a preferred choice in food and pharmaceutical formulations where precise pH control is required.
In food and beverage manufacturing, sodium malate regulates acidity in fruit-based products, confectionery, and soft drinks where a rounded, fruit-forward flavor profile is desired.
Pharmaceutical formulators use it as a buffering agent in oral liquid preparations and effervescent tablets to stabilize active ingredients across a defined pH range.
It functions as a flavor enhancer and acidity moderator in low-sodium seasoning blends and processed foods, where direct acidulants would be too aggressive.
In nutraceutical applications, it appears in mineral supplement formulations as a well-tolerated carrier salt. Sodium malate is supplied as a white crystalline powder or granules.
Food-grade material conforming to E350i specifications is the standard commercial form, with FCC -grade product available for applications requiring documented purity standards.
Pharmaceutical-grade supply meeting USP or Ph.Eur. specifications is available for regulated drug product manufacturing and high-purity industrial applications.
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Physical Properties
| Melting Point | >300°C (lit.) |
| Color | White to Almost white |
| Odor | at 100.00?%. odorless |
| Form | Liquid |
| Log P | -1.261 (est) |
Safety & Handling
Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 2918 19 98 |
| Storage Class | 13 - Non Combustible Solids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 676-46-0
- EC Number
- 211-627-6
- Mol. Weight
- 178.05
- HS Code
- 2918 19 98
- Category
- Salts & Minerals