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Salts & Minerals

Sodium malate

CAS: 676-46-0

Overview

Sodium malate (CAS 676-46-0 ), also known by its food additive designation E350i , is the disodium salt of malic acid used commercially as a pH buffer and acidulant.

It delivers a mild, smooth tartness without the sharp acidity of mineral acids, making it a preferred choice in food and pharmaceutical formulations where precise pH control is required.

In food and beverage manufacturing, sodium malate regulates acidity in fruit-based products, confectionery, and soft drinks where a rounded, fruit-forward flavor profile is desired.

Pharmaceutical formulators use it as a buffering agent in oral liquid preparations and effervescent tablets to stabilize active ingredients across a defined pH range.

It functions as a flavor enhancer and acidity moderator in low-sodium seasoning blends and processed foods, where direct acidulants would be too aggressive.

In nutraceutical applications, it appears in mineral supplement formulations as a well-tolerated carrier salt. Sodium malate is supplied as a white crystalline powder or granules.

Food-grade material conforming to E350i specifications is the standard commercial form, with FCC -grade product available for applications requiring documented purity standards.

Pharmaceutical-grade supply meeting USP or Ph.Eur. specifications is available for regulated drug product manufacturing and high-purity industrial applications.

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Physical Properties

Melting Point>300°C (lit.)
ColorWhite to Almost white
Odorat 100.00?%. odorless
FormLiquid
Log P-1.261 (est)

Safety & Handling

Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2918 19 98
Storage Class13 - Non Combustible Solids
WGK (Germany)3

Other Names

Malic aciddisodium salt | Disodium2-hydroxybutanedioate | Disodium malate | E350i

Related Products

Chemical Properties

CAS Number
676-46-0
EC Number
211-627-6
Mol. Weight
178.05
HS Code
2918 19 98

Industries

Documentation