5-chloro-2-methylaniline

CAS: 95-79-4

Overview

5-Chloro-2-methylaniline (CAS 95-79-4 ), also known as 5-chloro-o-toluidine and 2-amino-4-chlorotoluene, is an aromatic amine intermediate used in the synthesis of azo dyes, pigments, and specialty chemicals.

Its reactive amine group makes it a building block for colorant and polymer systems across multiple manufacturing sectors. In textile and leather dyeing, it functions as a diazonium coupling precursor for azo dye production.

This enables the manufacture of fast, vibrant colorants applied directly to fiber substrates. Pigment manufacturers use it to produce organic pigments incorporated into printing inks and packaging coatings.

Color strength and substrate adhesion are critical performance criteria in these applications. In polymer and plastics processing, it contributes to cross-linking and curing systems, improving structural integrity.

Personal care formulators sourcing approved colorant intermediates may evaluate it for cosmetic dye synthesis, subject to regional regulatory compliance. The material is supplied as a liquid or low-melting solid.

Physical state depends on purity and temperature conditions during handling. Technical grade is the standard commercial offering, with high-purity grades available for sensitive synthesis applications.

These high-purity options are ideal for processes requiring tighter specification control. Bulk and drum quantities are typical for industrial procurement, with smaller packaging available for laboratory use.

Physical Properties

Melting Point	26 °C
Boiling Point	237 °C @ Press: 722 Torr
Density	1.177 g/cm³ @ Temp: 20 °C
Flash Point	320 °F
Appearance	The chloromethylanilines are colorless or white crystalline solids or liquids, some have a mild fishy odor.
Color	Clear yellow to light brown
Form	Liquid After Melting
Water Solubility	< 1 g/L (22 ºC)
Vapor Pressure	0.45 hPa (50 °C)
Refractive Index	n 20/D 1.584(lit.)

Safety & Handling

Warning GHS07 GHS08 GHS09 Hazard Statements H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H320 Causes eye irritation H335 May cause respiratory irritation H351 Suspected of causing cancer H411 Toxic to aquatic life with long lasting effects H302+H312 Harmful if swallowed or in contact with skin Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code	29214300
UN Number	3429
ADR Class	6.1
Packing Group	III
Storage Class	6.1C - Combustible, acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)	3

Other Names

Industries

Printing & Packaging Plastics & Polymers Textile, Leather & Paper Personal Care & Cosmetics