Overview
2-Chloro-5-(trifluoromethyl)aniline (CAS 121-50-6 ), also known commercially as 3-Amino-4-chlorobenzotrifluoride or Fast Orange Salt RD, is an aromatic amine building block used across dye chemistry and agrochemical synthesis.
Its halogenated and trifluoromethyl-substituted structure makes it a targeted intermediate for constructing complex active molecules in pharmaceutical manufacturing. In the textile and leather industries, it functions as a diazonium coupling component.
This chemical is used to produce azo dyes with strong color fastness on fiber substrates. Agrochemical formulators use it as a key intermediate in synthesizing herbicides and fungicides where the trifluoromethyl group contributes to biological activity.
The trifluoromethyl group also provides metabolic stability in various applications. Pharmaceutical manufacturers incorporate it into API synthesis routes, particularly for compounds requiring a halogenated aniline scaffold for efficacy.
In coatings and adhesive systems, it supports the development of specialty resins and crosslinked polymer matrices with targeted performance profiles. This versatile chemical is supplied as a liquid or low-melting solid for industrial use.
It is typically available in technical and synthesis grades to meet diverse manufacturing requirements. It is available in packaging ranging from laboratory quantities to bulk drums for large-scale industrial procurement needs.
Purity specifications commonly range from 98% to 99%+ by GC, with documentation supporting pharmaceutical and agrochemical intermediate applications. Quality control ensures consistency across all batches for high-performance results.
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Physical Properties
| Melting Point | 10 °C |
| Boiling Point | 57-58 °C @ Press: 1.5 Torr |
| Density | 1.428 g/mL at 25 °C(lit.) |
| Flash Point | 75 °C |
| Appearance | CLEAR COLORLESS TO LIGHT YELLOW LIQUID |
| Color | Colorless to Yellow to Green |
| Form | clear liquid |
| Water Solubility | 11 g/L (60 ºC) |
| Vapor Pressure | 0.15 hPa |
| Refractive Index | n 20/D 1.499(lit.) |
Safety & Handling
Warning GHS07 GHS09 Hazard Statements H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H332 Harmful if inhaled H411 Toxic to aquatic life with long lasting effects Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29214300 |
| UN Number | 2810 |
| ADR Class | 6.1 |
| Packing Group | III |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 2 |
Other Names
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Chemical Properties
- CAS Number
- 121-50-6
- EC Number
- 204-475-7
- Mol. Weight
- 195.57
- HS Code
- 29214300
- Category
- Amines