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Heterocyclic Compounds

Isothiazolinone

CAS: 1003-07-2

Overview

Isothiazolinone (CAS 1003-07-2 ), also referred to as 3-Isothiazolone, is the core heterocyclic scaffold underlying a broad class of industrial biocides and preservatives.

It functions as the active structural basis for formulated antimicrobial agents used across water-based systems, personal care products, and industrial process fluids.

In personal care and cosmetics, isothiazolinone-based actives are incorporated into rinse-off and leave-on formulations to control microbial growth and extend shelf life.

Pulp and paper manufacturers use isothiazolinone chemistry to prevent slime-forming bacteria and fungi in process water and coating systems for industrial use.

In metalworking and lubricant fluids, it controls microbial contamination that would otherwise degrade fluid performance and corrode equipment during manufacturing.

Water treatment and oil and gas operations rely on isothiazolinone-derived biocides to manage biofilm formation in cooling towers, injection water, and produced water streams.

Isothiazolinone is supplied as a technical-grade material, typically as a liquid concentrate or aqueous solution, and is commonly blended into formulated biocide products.

Concentration levels in commercial blends vary depending on the target application and regulatory requirements. Technical-grade specifications are standard for industrial supply.

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Physical Properties

Melting Point73-74 °C
Density1.366±0.06 g/cm3(Predicted)
ColorOff-White
FormSolid

Safety & Handling

Warning GHS07 Hazard Statements H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2934100090

Other Names

3-Isothiazolone | Isothiazolin-3-one | E57JT172V7 | RefChem:792369 | Isothiazol-3(2H)-one | 3(2H)-Isothiazolone | Isothiazol-3-one

Related Products

Chemical Properties

CAS Number
1003-07-2
EC Number
696-206-9
Mol. Weight
101.13
HS Code
2934100090

Industries

Documentation