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Pharmaceutical Intermediates

4-hydroxybenzaldehyde

CAS: 123-08-0

Overview

4-Hydroxybenzaldehyde (CAS 123-08-0 ), commonly referred to as 4-HBA or p-hydroxybenzaldehyde, is a phenolic aldehyde used as a key synthetic intermediate and flavoring agent across pharmaceutical, food, and cosmetic manufacturing.

FEMA 3984 status supports its use in flavor applications where regulatory traceability is required. In pharmaceutical manufacturing, 4-HBA serves as a precursor in the synthesis of active ingredients.

It is used in the production of antiviral compounds and vanillin derivatives, making it a recurring procurement target for API producers. Food and beverage formulators source it as a flavoring component.

Its natural phenolic character contributes to vanilla-adjacent profiles in various food products. In personal care, it functions as a UV stabilizer and preservative booster in skin and hair formulations.

Polymer and resin producers also use it as a building block for UV-stabilizing additives and specialty antioxidant systems. 4-Hydroxybenzaldehyde is supplied as a white to off-white crystalline solid.

Standard commercial grades include technical and pharmaceutical-grade material, with high-purity specifications available to meet API intermediate requirements. FCC -grade material is available for flavor applications.

This grade is essential for food applications requiring documented food safety compliance. The material is handled according to strict quality protocols to ensure consistency across global supply chains.

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Physical Properties

Melting Point117 °C
Boiling Point109 °C
Density1.35 g/cm³ (liquid) @ Temp: 20 °C
Flash Point174°C
Appearanceyellow to light brown crystalline powder
Colorlight yellow to light brown
Odorat 100.00 %. sweet nutty almond balsam woody
FormCrystalline Powder
Water Solubility13 g/L (30 ºC)
Vapor Pressure0.004Pa at 25℃
Refractive Index1.5105 (estimate)
Log P1.3 at 23℃

Trade & Regulatory

HS Code29124900
Storage Class11 - Combustible Solids
WGK (Germany)2

Other Names

Usaf m-6 | p-oxybenzaldehyde | p-hydroxybenzaldehyde | p-formylphenol | 4-hydroxybenzenecarbonal | 4-formylphenol | Benzaldehyde4-hydroxy- | Para-Hydroxybenzaldehyde | 4-HBA

Related Products

Chemical Properties

CAS Number
123-08-0
EC Number
204-599-1
Mol. Weight
122.12
HS Code
29124900

Industries

Documentation