Overview
4-Biphenylaldehyde (CAS 3218-36-8 ), also known as 4-biphenylcarboxaldehyde, is an aromatic aldehyde used as a synthetic building block in specialty chemical manufacturing.
Its biphenyl-aldehyde structure makes it a valued intermediate for constructing complex organic molecules across polymer, fragrance, and fine chemical applications.
In polymer and materials chemistry, it serves as a monomer or crosslinking intermediate for engineering specialty resins and liquid crystal polymers where rigid aromatic backbones are required.
Fragrance formulators incorporate it into fine fragrance and cosmetic compositions for its floral-aldehyde character, particularly in applications targeting premium personal care products.
In pharmaceutical and agrochemical synthesis, it functions as a key intermediate for constructing biphenyl-containing active compounds for various industrial research purposes.
Printing and packaging chemists also utilize it in the development of photoinitiator systems and UV-curable ink formulations to enhance performance in specialized coating applications.
4-Biphenylaldehyde is supplied as a white to off-white crystalline solid. It is commercially available at 99% purity, which is the standard specification for synthesis-grade procurement.
Packaging is typically offered in gram to kilogram quantities, reflecting its primary positioning as a fine chemical intermediate rather than a bulk commodity for industrial use.
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Physical Properties
| Melting Point | 60-61 °C |
| Boiling Point | 130 °C @ Press: 0.5 Torr |
| Density | 1,107 g/cm 3 |
| Flash Point | 172°C |
| Appearance | WHITE TO LIGHT YELLOW CRYSTALS OR CRYST. POWDER |
| Color | White to light yellow |
| Form | Crystals or Crystalline Powder |
| Water Solubility | 17mg/L at 20℃ |
| Vapor Pressure | 0.025Pa at 25℃ |
| Refractive Index | 1.5994 (estimate) |
| Log P | 2.98 at 20℃ |
Safety & Handling
Warning GHS07 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29122990 |
| WGK (Germany) | 1 |
Other Names
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Chemical Properties
- CAS Number
- 3218-36-8
- EC Number
- 221-742-3
- Mol. Weight
- 182.22
- HS Code
- 29122990
- Category
- Monomers & Building Blocks