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Vitamins & Nutrients

Butylated Hydroxyanisole

CAS: 25013-16-5

Overview

Butylated Hydroxyanisole ( CAS 25013-16-5 ), commonly known as BHA or E320 , is a synthetic phenolic antioxidant used across food, cosmetic, pharmaceutical, and industrial applications.

It prevents oxidative degradation in fats, oils, and lipid-containing formulations, extending shelf life and maintaining product integrity. In food manufacturing, BHA is approved under E320 and FEMA 2183 .

It is used in edible fats, oils, snack foods, and packaging materials where fat oxidation is a primary spoilage concern. Cosmetic and personal care formulators incorporate it into creams and lotions.

These products stabilize oil-phase ingredients against rancidity. Pharmaceutical manufacturers use it to protect lipid excipients and active ingredients in oral and topical dosage forms to ensure stability.

In plastics, rubber, and lubricant production, BHA functions as a processing stabilizer. It protects polymer matrices and petroleum-based fluids from oxidative breakdown during manufacturing and storage.

BHA is supplied as a white to off-white waxy solid, typically in flake or powder form. It is available in food-grade specifications conforming to FCC , BP , and Ph. Eur. standards.

Technical grade options are also available for industrial applications. Purity levels of 98.5% and above are standard for regulated food and pharmaceutical supply chains to ensure high performance.

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Physical Properties

Melting Point48-55 °C
Boiling Point264-270 °C @ Press: 733 Torr
Density0.9976 (rough estimate)
Flash Point>230 °F
AppearanceLog Kow 5. 3. Values above 3.0 are likely to bioaccumulate in aquatic organisms
ColorWhite to pale yellow
Odormild rubbery
FormCrystalline Flakes or Crystals
Water Solubility<0.1 g/100 mL at 18.5 ºC
Refractive Index1.4910 (estimate)
Log P3.00

Safety & Handling

Warning GHS07 GHS08 GHS09 Hazard Statements H302 Harmful if swallowed H303 May be harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H335 May cause respiratory irritation H336 May cause drowsiness or dizziness H351 Suspected of causing cancer H361 Suspected of damaging fertility or the unborn child H371 May cause damage to organs H401 Toxic to aquatic life H411 Toxic to aquatic life with long lasting effects Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P318 IF exposed or concerned, get medical advice. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P308+P316 Get emergency medical help immediately. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29093090
Storage Class11 - Combustible Solids
WGK (Germany)2

Other Names

tert-Butylhydroxyanisole | 2-tert-butyl-4-methoxyphenol | BHA | E320

Related Products

Chemical Properties

CAS Number
25013-16-5
EC Number
246-563-8
Mol. Weight
180.24
HS Code
29093090

Industries

Documentation