Propylparaben

CAS: 94-13-3

Overview

Propylparaben (CAS 94-13-3 ), also sold under trade names Tegosept P, Solbrol P, and Protaben P, is a synthetic preservative approved as E216 across food, cosmetic, and pharmaceutical applications.

It inhibits the growth of mold, yeast, and bacteria at low concentrations, making it one of the most cost-effective broad-spectrum antimicrobial options available to formulators today.

In personal care and cosmetics, it is used to preserve lotions, shampoos, and creams against microbial contamination throughout shelf life. This ensures product safety and maintains integrity for consumers.

Pharmaceutical manufacturers incorporate it as a preservative in oral suspensions, topical preparations, and multi-dose injectable formulations where microbial control is a strict regulatory requirement.

Food and beverage producers apply it under the E216 designation to protect baked goods, sauces, and beverages. It is often used in combination with methylparaben for broader efficacy and protection.

In coatings and adhesive systems, it functions as a biocide to prevent microbial degradation during storage and application. This helps maintain the physical properties of industrial chemical mixtures.

Propylparaben is supplied as a white crystalline powder. Standard grades include USP , BP , Ph. Eur. , and FCC , covering pharmaceutical, cosmetic, and food-grade procurement requirements.

Technical grade is also available for industrial applications such as coatings and adhesive systems. These high-purity standards ensure consistent performance across all manufacturing sectors.

Physical Properties

Melting Point	96-97 °C
Boiling Point	294 °C
Density	1.0630 g/cm³ @ Temp: 102 °C
Flash Point	180°(356°F)
Appearance	white crystalline powder
Color	White
Odor	at 100.00 %. sweet smoky burnt woody hawthorn
Form	Crystalline Powder
Water Solubility	<0.1 g/100 mL at 12 ºC
Vapor Pressure	0.67 hPa (122 °C)
Refractive Index	1.5050
pH	6-7 (H2O, 20°C) (saturated solution)
Log P	2.8 at 20℃

Safety & Handling

Warning GHS07 GHS08 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H335 May cause respiratory irritation H370 Causes damage to organs H373 May causes damage to organs through prolonged or repeated exposure H401 Toxic to aquatic life Precautionary Statements P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P308+P316 Get emergency medical help immediately. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code	29182930
WGK (Germany)	1

Other Names

Industries

Coatings, Adhesives, Sealants & Elastomers Food & Nutrition Personal Care & Cosmetics Pharmaceuticals & Healthcare