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Pharmaceutical Intermediates

Climbazole

CAS: 38083-17-9

Overview

Climbazole (CAS 38083-17-9 ), also known by the trade names Baypival and Crinipan AD, is an imidazole-based antifungal active used across personal care, pharmaceutical, and industrial applications.

It targets fungal growth, particularly Malassezia species, making it a standard active ingredient in anti-dandruff and scalp treatment formulations for various consumer products.

In personal care, this compound is incorporated into shampoos, conditioners, and scalp serums at low concentrations to control dandruff-causing fungi and maintain healthy scalp conditions.

Pharmaceutical formulators use it as an active or intermediate in topical antifungal preparations targeting dermatological conditions. It is highly effective in specialized medical skin care treatments.

In textile and leather processing, it functions as a biocide to prevent mold and fungal degradation during storage and finishing. This ensures the longevity and quality of raw materials.

Paper manufacturers apply it as a preservative treatment to protect against fungal spoilage in humid storage environments. This application is critical for maintaining structural integrity in industrial settings.

The material is supplied as a white to off-white crystalline powder. Standard commercial grades include technical and cosmetic-grade material, with purity specifications typically at 98% or higher by HPLC.

Packaging is available in kilogram quantities for formulators and larger bulk formats for industrial buyers. We ensure all batches meet rigorous internal quality control and safety protocols.

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Physical Properties

Melting Point98.000 °C
Boiling Point447.5±40.0 °C(Predicted)
Density1.17±0.1 g/cm3(Predicted)
ColorWhite to Almost white
Formneat
Water Solubility58mg/L at 25℃
Vapor Pressure0.001Pa at 25℃
Refractive Index1.54
Log P3.83 at 25℃

Safety & Handling

Warning GHS07 GHS09 Hazard Statements H302 Harmful if swallowed H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects H412 Harmful to aquatic life with long lasting effects Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P330 Rinse mouth. P391 Collect spillage. P501 Dispose of contents/container in accordance with local regulations. P301+P317 Get emergency medical help.

Trade & Regulatory

HS Code29332900
UN Number3077
Storage Class13 - Non Combustible Solids
WGK (Germany)3

Other Names

Climbazol | Baypival | Crinipan AD | BAY-E 6975 | Baysan | 2-Butanone1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-33-dimethyl- | 1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-33-dimethyl-2-butanone | 1-[(4-Chlorophenoxy)(tert-butylcarbonyl)methyl]imidazole

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Chemical Properties

CAS Number
38083-17-9
EC Number
253-775-4
Mol. Weight
292.76
HS Code
29332900

Industries

Documentation