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Pigments & Colorants

1-bromo-4-iodobenzene

CAS: 589-87-7

Overview

1-Bromo-4-iodobenzene (CAS 589-87-7 ), also known as p-bromoiodobenzene, is a dual-halogenated aromatic building block used across pharmaceutical synthesis and specialty chemical manufacturing.

The presence of two distinct halogen substituents on the benzene ring allows selective cross-coupling reactions, making it a practical starting material for constructing complex molecular architectures.

In pharmaceutical intermediate synthesis, it serves as a key precursor in palladium-catalyzed reactions where chemists exploit the differential reactivity of bromine and iodine to achieve regioselective functionalization.

Polymer and materials chemists use it to introduce halogenated aryl units into flame-retardant polymer systems, particularly where controlled halogen loading is required for specific industrial applications.

In dye and pigment manufacturing, it functions as a reactive intermediate for producing brominated and iodinated aromatic colorants used in various textile and leather applications across the globe.

It also supports the development of specialty monomers and cross-linkers in advanced polymer formulations targeting specific thermal or electronic performance profiles for high-tech manufacturing sectors.

1-Bromo-4-iodobenzene is supplied as a white to off-white crystalline solid. It is available in technical and high-purity grades, with purity levels typically ranging from 98% to 99%+ for fine chemical synthesis.

Packaging options generally range from small laboratory quantities up to multi-kilogram lots for industrial procurement, ensuring reliable supply chains for both research and large-scale production needs.

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Physical Properties

Melting Point92 °C
Boiling Point90 °C
Density2.2236 (rough estimate)
Flash Point120-122°C/14mm
Appearancewhite to brown cryst. powder, crystals or needles
ColorWhite to brown
FormCrystalline Powder, Crystals or Needles
Water SolubilityInsoluble in water.
Refractive Index1.6618 (estimate)

Safety & Handling

Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H413 May cause long lasting harmful effects to aquatic life Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29036990
Storage Class11 - Combustible Solids
WGK (Germany)3

Other Names

p-Bromoiodobenzene | Benzene1-bromo-4-iodo- | 4-bromo-1-iodobenzene | 4-iodobromobenzene | 4-bromophenyl iodide | 4-iodo-1-bromobenzene | R9LDG2XS7C

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Chemical Properties

CAS Number
589-87-7
EC Number
209-662-7
Mol. Weight
282.90
HS Code
29036990

Industries

Documentation