Procaine

Procaine (CAS 59-46-1 ), also known commercially as Vitamin H3, is a synthetic local anesthetic active pharmaceutical ingredient with a long-established history in medical and pharmaceutical manufacturing.

It functions as a nerve-blocking agent, temporarily inhibiting pain signal transmission at the site of administration. In pharmaceutical manufacturing, it is used as the active ingredient in injectable local anesthetic formulations.

This compound is particularly vital for dental and minor surgical procedures. It serves as a starting material or reference compound in the synthesis of next-generation anesthetic derivatives and pharmaceutical intermediates.

Compounding pharmacies source this material for the preparation of specialized injectable solutions where longer-acting agents are contraindicated. Research and analytical laboratories also procure it as a reference standard.

It is essential for method validation and quality control testing of anesthetic formulations. The product is supplied as a white crystalline powder in both free base and hydrochloride salt forms.

The hydrochloride salt is the predominant commercial form due to its water solubility. Standard grades available in the market include USP , BP , and Ph. Eur. , supporting use in regulated manufacturing.

Bulk quantities are typically offered for industrial API production, with smaller quantities available for laboratory and compounding applications. This ensures a steady supply for various professional medical requirements.

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