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Catalysts & Catalyst Precursors

Nicotinic acid

CAS: 59-67-6

Overview

Nicotinic acid (CAS 59-67-6 ), also known commercially as E375 and Niacin, is a water-soluble B-vitamin (B3) used across food, pharmaceutical, and personal care manufacturing. It functions as a nutrient fortifier, acidulant, and catalyst precursor depending on the application sector.

In food and beverage manufacturing, nicotinic acid is approved for flour and cereal fortification, restoring B-vitamin content lost during processing. Pharmaceutical producers use it as an active ingredient in vitamin B3 supplements and as a precursor in the synthesis of nicotinamide.

In personal care formulations, it supports skin-conditioning actives, particularly in products targeting uneven tone and barrier function. Specialty chemical manufacturers also employ it as a ligand or precursor in catalyst systems for organic synthesis processes.

Nicotinic acid is supplied as a white crystalline powder. Standard grades include USP , BP , Ph. Eur. , and food-grade specifications, with food-grade material conforming to purity requirements for direct food contact applications.

FCC -grade material is available for North American food and dietary supplement markets. This ensures compliance with strict safety standards across various global jurisdictions and industrial requirements for high-purity chemical sourcing.

The material is also available in EP and Ph.Eur. compliant forms to meet European pharmaceutical standards. These certifications guarantee the chemical integrity and consistency required for sensitive manufacturing environments and large-scale production.

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Physical Properties

Melting Point236.6 °C
Boiling Point279-305 °C
Density1.473 g/cm³ @ Temp: 25 °C
Flash Point193°C
AppearanceWhite powder
ColorWhite to off-white
Odorodorless to sl. odor, sour taste
FormPowder
Water Solubility1-5 g/100 mL at 17 ºC
Refractive Index1.5423 (estimate)
pH2.7 (18g/l, H2O, 20℃)
Log P0.360

Safety & Handling

Warning GHS07 Hazard Statements H319 Causes serious eye irritation H402 Harmful to aquatic life Precautionary Statements P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29362990
UN Number1230
Packing GroupII
Storage Class11 - Combustible Solids
WGK (Germany)1

Other Names

β-pyridinecarboxylic acid | Wampocap | Tinic | Slo-niacin | Pyridine-beta-carboxylic acid | pyridine-3-carboxylic acid | Peviton | Pelonin | E375

Related Products

Chemical Properties

CAS Number
59-67-6
EC Number
200-441-0
Mol. Weight
123.11
HS Code
29362990

Industries

Documentation