Overview
Ethyl nicotinate (CAS 614-18-6 ), also known commercially as Ignicut, is the ethyl ester of nicotinic acid used as a pharmaceutical intermediate, flavoring agent, and functional ingredient across multiple industries.
It serves as a building block in the synthesis of active pharmaceutical ingredients and as a precursor in catalyst systems. In pharmaceutical manufacturing, it functions as a key intermediate in the synthesis of niacin derivatives.
Other nicotinic acid-based APIs utilize this compound where ester reactivity drives efficient conversion pathways. Cosmetic formulators incorporate it into topical products targeting skin circulation effects, particularly in warming formulations.
As a flavoring agent, it contributes to tobacco and food flavor profiles where pyridine-type notes are required. It carries a recognized FEMA status supporting its use in regulated flavor applications worldwide.
In catalyst development, it acts as a ligand precursor or coordination compound in heterogeneous and homogeneous catalytic systems. The material is available as a colorless to pale yellow liquid in standard commercial packaging.
It is supplied in pharmaceutical-grade and technical-grade specifications to meet the purity requirements of API synthesis. Certificates of analysis aligned with USP and BP standards are commonly available.
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Physical Properties
| Melting Point | 8.5 °C |
| Boiling Point | 121-123 °C @ Press: 0.4 Torr |
| Density | 1.5117 g/cm³ @ Temp: 20 °C |
| Flash Point | 93 °C |
| Appearance | clear colourless to yellow liquid |
| Color | light yellow |
| Form | neat |
| Water Solubility | miscible |
| Vapor Pressure | 4.2-5.5Pa at 20-25℃ |
| Refractive Index | n 20/D 1.504(lit.) |
| Log P | 1.32 |
Safety & Handling
Warning GHS07 Hazard Statements H319 Causes serious eye irritation Precautionary Statements P280 Wear protective gloves/protective clothing/eye protection/face protection. P264+P265 Wash … thoroughly after handling. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29333999 |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 614-18-6
- EC Number
- 210-370-7
- Mol. Weight
- 151.16
- HS Code
- 29333999
- Category
- Catalysts & Catalyst Precursors