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Heterocyclic Compounds

DMDM hydantoin

CAS: 6440-58-0

Overview

DMDM hydantoin (CAS 6440-58-0 ), also marketed under the trade name Glydant, is a formaldehyde-releasing preservative used to prevent microbial contamination in aqueous formulations.

DMDMH delivers broad-spectrum antimicrobial activity against bacteria, yeast, and mold across a wide range of product types. In personal care and cosmetics, it is used to preserve rinse-off and leave-on products.

This includes shampoos, conditioners, body washes, and lotions, where water activity creates high microbial risk. Industrial coating and adhesive formulations rely on it as an in-can preservative to extend shelf life.

It prevents spoilage during storage and transport for water-based paints, sealants, and latex systems. These systems incorporate DMDMH to protect against bacterial and fungal degradation that would compromise viscosity.

It is also used in wet-state preservation of adhesive and elastomer compounds where conventional biocides lack sufficient water compatibility. This ensures long-term stability in complex chemical mixtures.

DMDM hydantoin is supplied as a clear aqueous solution, typically at 55% active concentration. It is available in cosmetic-grade and technical-grade specifications to meet the requirements of various applications.

Packaging options generally range from drums to intermediate bulk containers (IBCs) for industrial volumes. Our material meets rigorous quality benchmarks to ensure consistent performance in every batch.

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Physical Properties

Melting Point98-100 °C
Boiling Point303.7±52.0 °C(Predicted)
Density1.349±0.06 g/cm3(Predicted)
AppearanceLiquid
ColorWhite to Off-White
FormSolid
Water Solubility140g/L at 20℃
Vapor Pressure0Pa at 25℃
Log P-2.9 at 20℃

Safety & Handling

Danger GHS07 GHS08 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Precautionary Statements P233 Keep container tightly closed. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. P284 In case of inadequate ventilation wear respiratory protection. P321 Specific treatment (see … on this label). P330 Rinse mouth. P403 Store in a well-ventilated place. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P333+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P342+P316 Get emergency medical help immediately. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29339900
Storage Class10 - Combustible liquids
WGK (Germany)3

Other Names

Dmdmh | Glydant | 13-Bis(hydroxymethyl)-55-dimethylhydantoin | 13-Dimethylol-55-dimethylhydantoin | Dantoin-DMDMH | Glycoserve-DMDMH | Dantoin dmdmh 55 | Dimethylol-55-dimethylhydantoin

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Chemical Properties

CAS Number
6440-58-0
EC Number
229-222-8
Mol. Weight
188.18
HS Code
29339900

Industries

Documentation