Overview
Quinine sulfate (CAS 804-63-7 ) is the sulfate salt form of quinine, also marketed as quinine sulphate, used primarily in pharmaceutical manufacturing and analytical research. Supplied as a stable, water-soluble solid, it offers reliable handling and consistent purity for regulated production environments.
In pharmaceutical manufacturing, this compound serves as the active ingredient in oral dosage forms targeting nocturnal leg cramps and malaria treatment in regulated markets. Analytical and QC laboratories use it as a fluorescence standard for calibrating spectrophotometers.
The material is essential for validating UV detection systems, given its well-characterized emission profile. In the food and beverage industry, it functions as a bittering agent in tonic waters and carbonated drinks under FEMA 2977 .
Precise dosing is required to meet regulatory bitterness thresholds in commercial beverage production. Biotechnology researchers also use it in cell biology assays and as a reference compound in pharmacokinetic studies for drug development.
Quinine sulfate is available as a white to off-white crystalline powder in both anhydrous and dihydrate forms. Standard grades include USP , BP , and Ph. Eur. , supporting use in GMP-regulated pharmaceutical production.
Research and reagent-grade material is also available for laboratory and analytical applications. These high-purity options ensure consistent results across various industrial and scientific workflows while meeting strict international quality benchmarks.
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Physical Properties
| Melting Point | 235.2 °C |
| Density | 1.0807 (rough estimate) |
| Color | White to off-white |
| Odor | wh. fine needle-like cryst., odorless, very bitter taste |
| Form | Solid |
| Refractive Index | 1.6000 (estimate) |
| Log P | 3.44 |
Safety & Handling
Warning GHS07 Hazard Statements H302 H302 H315 H315 H317 H317 H319 H319 H335 H335 Precautionary Statements P261 P261 P264 P264 P270 P270 P271 P271 P272 P272 P280 P280 P319 P319 P321 P321 P330 P330 P405 P405 P501 P501 P264+P265 P264+P265 P301+P317 P301+P317 P302+P352 P302+P352 P304+P340 P304+P340 P332+P317 P332+P317 P333+P317 P333+P317 P337+P317 P337+P317 P362+P364 P362+P364 P403+P233 P403+P233 P305+P351+P338 P305+P351+P338
Trade & Regulatory
| HS Code | 29339900 |
Other Names
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Chemical Properties
- CAS Number
- 804-63-7
- EC Number
- 212-359-1
- Mol. Weight
- 746.9
- HS Code
- 29339900
- Category
- Pharmaceutical Intermediates