Overview
2-Methylquinoline (CAS 91-63-4 ), commercially recognized as Quinaldine, is a nitrogen-containing heterocyclic compound used across pharmaceutical synthesis, dye manufacturing, and specialty chemical production.
It functions primarily as a building block and intermediate, enabling the construction of more complex active molecules and functional materials. In pharmaceutical manufacturing, it serves as a key synthetic intermediate.
This includes the production of antimalarial compounds, including quinine derivatives, and other bioactive heterocyclic APIs. Polymer and plastics producers use it as a stabilizer and antioxidant precursor.
It is particularly useful in formulations requiring protection against thermal degradation. In dye and pigment chemistry, it contributes to the synthesis of quinoline yellow and related colorants.
These colorants are used in food-contact and industrial coating applications. Flavor and fragrance formulators incorporate it at controlled concentrations where its characteristic quinoline note is required.
2-Methylquinoline is supplied as a liquid at ambient conditions, typically offered in technical and high-purity grades suited to pharmaceutical intermediate and specialty chemical applications.
Standard purity levels of 98% and above are commonly available for research and industrial procurement. Packaging ranges from small laboratory quantities through to drum volumes for global shipping.
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Physical Properties
| Melting Point | -1.5 °C |
| Boiling Point | 80-81 °C @ Press: 2 Torr |
| Density | 1.0600 g/cm³ @ Temp: 20 °C |
| Flash Point | 175 °F |
| Appearance | yellowish-brown liquid |
| Color | White to slightly yellow |
| Form | Crystalline Powder |
| Water Solubility | PRACTICALLY INSOLUBLE |
| Vapor Pressure | <0.1 hPa (20 °C) |
| Refractive Index | n 20/D 1.612(lit.) |
| pH | 6.9 (H2O, 20℃)(saturated aqueous solution) |
| Log P | 2.59 |
Safety & Handling
Warning GHS07 GHS08 Hazard Statements H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H319 Causes serious eye irritation H341 Suspected of causing genetic defects H412 Harmful to aquatic life with long lasting effects H302+H312 Harmful if swallowed or in contact with skin Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P318 IF exposed or concerned, get medical advice. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29334990 |
| Packing Group | III |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 91-63-4
- EC Number
- 202-085-1
- Mol. Weight
- 143.18
- HS Code
- 29334990
- Category
- Flavors & Fragrances