Overview
Ibuprofen (CAS 15687-27-1 ) is a non-steroidal anti-inflammatory active pharmaceutical ingredient used across prescription and OTC drug manufacturing globally. Sourced in bulk API form, it functions as the primary analgesic agent.
The largest commercial demand comes from OTC tablet and capsule production, where it is the active ingredient in pain relief and fever reduction products. Liquid suspension manufacturing represents a distinct high-volume segment.
These pediatric formulations require specific particle size and solubility profiles to ensure efficacy. Topical pharmaceutical products, including gels and creams for localized pain, rely on defined concentrations for transdermal delivery.
Contract manufacturers and generic drug producers also source this material as a starting material or intermediate. It is frequently used in the synthesis of ibuprofen lysinate and other specialized salt-form derivatives.
The product is supplied as a white crystalline powder in bulk quantities, typically ranging from kilogram to multi-tonne lots. Standard grades include USP , BP , Ph.Eur. , and JP for global compliance.
Grade selection is driven by the target market's regulatory requirements and specific formulation needs. Micronized grades are available for applications where enhanced dissolution rate or suspension uniformity is a priority.
Contact us for supply of Ibuprofen
Physical Properties
| Melting Point | 75-77 °C |
| Boiling Point | 307.30 °C |
| Density | 0.453 g/cm³ (bulk) |
| Flash Point | 9°C |
| Appearance | Colourless, Crystalline Solid |
| Color | white to off-white |
| Form | Crystalline Powder |
| Water Solubility | insoluble |
| Refractive Index | 1.5500 (estimate) |
| Log P | 3.970 |
Safety & Handling
Warning GHS07 GHS08 GHS09 Hazard Statements H302 Harmful if swallowed H319 Causes serious eye irritation H335 May cause respiratory irritation H360 May damage fertility or the unborn child H361 Suspected of damaging fertility or the unborn child H362 May cause harm to breast-fed children H371 May cause damage to organs H373 May causes damage to organs through prolonged or repeated exposure H411 Toxic to aquatic life with long lasting effects Precautionary Statements P203 Obtain, consult and follow expert instructions for use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P263 Avoid contact during pregnancy and while nursing. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P318 IF exposed or concerned, get medical advice. P319 Get medical advice/attention if you feel unwell. P330 Rinse mouth. P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P308+P316 Get emergency medical help immediately. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29163920 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
Related Products
Chemical Properties
- CAS Number
- 15687-27-1
- EC Number
- 239-784-6
- Mol. Weight
- 206.28
- HS Code
- 29163920
- Category
- Flavors & Fragrances