Overview
Sodium methylparaben (CAS 5026-62-0 ), also known by its EU food additive designation E219 , is the sodium salt form of methylparaben used as a broad-spectrum antimicrobial preservative.
Its water-soluble nature makes it the preferred paraben variant for aqueous-based formulations across pharmaceuticals, personal care, and food applications. In pharmaceutical manufacturing, it protects liquid oral preparations.
It is also utilized in topical creams and injectable formulations against microbial contamination throughout shelf life. Personal care formulators incorporate it into shampoos, lotions, and wet wipes where water activity creates spoilage risk.
As E219, it is permitted in select food categories to extend product stability, particularly in processed foods and beverages where alternative preservatives may affect taste or regulatory standing.
Coating and adhesive systems with aqueous carrier phases also use it to prevent in-can microbial growth during storage and distribution. Sodium methylparaben is supplied as a white crystalline powder or fine granules.
It is available in USP , BP , and Ph. Eur. grades for pharmaceutical and personal care applications. Food-grade material meeting E219 specifications is also available for regulated food use.
Technical grade is also available for industrial coating and adhesive applications. This ensures compatibility across a wide range of manufacturing requirements and global regulatory standards for chemical safety.
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Physical Properties
| Melting Point | >125°C |
| Density | 1.42 g/cm3 (20 °C) |
| Appearance | white powder |
| Color | White |
| Form | Powder |
| Water Solubility | 418g/L at 20℃ |
| pH | 9.7-10.3 (1g/l, H2O) |
| Log P | -0.63 at 20℃ |
Safety & Handling
Danger GHS05 GHS07 GHS09 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H411 Toxic to aquatic life with long lasting effects H412 Harmful to aquatic life with long lasting effects Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P321 Specific treatment (see … on this label). P330 Rinse mouth. P391 Collect spillage. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P332+P317 Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29182930 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Other Names
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Chemical Properties
- CAS Number
- 5026-62-0
- EC Number
- 225-714-1
- Mol. Weight
- 174.13
- HS Code
- 29182930
- Category
- Pharmaceutical Intermediates