Overview
Methylparaben (CAS 99-76-3 ), also known as Tegosept M, is a synthetic antimicrobial preservative used across pharmaceutical, cosmetic, and food manufacturing. It inhibits the growth of bacteria, yeast, and mold in finished formulations.
This chemical extends product shelf life at low use concentrations. In pharmaceutical manufacturing, it preserves oral suspensions, topical creams, and injectable preparations where microbial contamination control is a regulatory requirement.
Personal care producers rely on it to protect lotions, shampoos, and makeup products from spoilage throughout their shelf life. Food and beverage manufacturers apply it under FEMA 2710 designation to protect goods.
It is commonly used in processed goods, beverages, and flavoring systems. It also functions as a UV stabilizer in certain formulations, protecting active ingredients from photodegradation during storage and transport.
Methylparaben is supplied as a white crystalline powder. Standard grades include USP , BP , Ph. Eur. , and FCC , covering pharmaceutical, cosmetic, and food-grade procurement requirements for global supply chains.
Technical grade is available for industrial preservation applications where compendial certification is not required. This versatile preservative remains a staple for ensuring product safety and stability across multiple industries.
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Physical Properties
| Melting Point | 131 °C |
| Boiling Point | 265 °C |
| Density | 1.383 g/cm³ (crystalline) @ Temp: 25 °C; Press: 750 Torr |
| Flash Point | 280°C |
| Appearance | white crystalline powder |
| Color | White to almost white |
| Odor | odorless or faint char. odor, sl. burning taste |
| Form | Crystalline Powder |
| Water Solubility | Slightly soluble in water. |
| Vapor Pressure | 0.000005 hPa (20 °C) |
| Refractive Index | 1.4447 (estimate) |
| pH | 5.8 (H2O, 20°C) (saturated solution) |
| Log P | 1.98 at 20℃ |
Safety & Handling
Warning GHS07 GHS09 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H336 May cause drowsiness or dizziness H402 Harmful to aquatic life H411 Toxic to aquatic life with long lasting effects H412 Harmful to aquatic life with long lasting effects Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P391 Collect spillage. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29182930 |
| UN Number | 2769 |
| WGK (Germany) | 1 |
Other Names
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Chemical Properties
- CAS Number
- 99-76-3
- EC Number
- 202-785-7
- Mol. Weight
- 152.15
- HS Code
- 29182930
- Category
- Flavors & Fragrances