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Pharmaceutical Intermediates

Benzylparaben

CAS: 94-18-8

Overview

Benzylparaben (CAS 94-18-8 ), also known as Benzyl p-hydroxybenzoate, is a paraben-series preservative used across cosmetics, pharmaceuticals, and food-contact applications. It inhibits microbial growth in formulations where longer chain parabens are preferred.

These longer chain parabens are valued for their enhanced lipophilicity and oil-phase compatibility. In cosmetics and personal care, it functions as a broad-spectrum preservative in creams, lotions, and emulsions.

It is particularly effective in oil-rich or anhydrous systems where water-soluble preservatives underperform. Pharmaceutical formulators incorporate it to protect topical preparations, ointments, and some oral dosage forms.

This protection prevents bacterial and fungal contamination during the product shelf life. Its UV-stabilizing activity makes it relevant in formulations requiring secondary antioxidant or photostabilizer support.

It is often used alongside primary UV filters to maintain product integrity. As a flavoring agent, it appears in fragrance and flavor compositions at controlled use levels to enhance specific profiles.

Benzylparaben is supplied as a white crystalline powder for industrial use. Standard grades include cosmetic/technical and pharmaceutical-grade material meeting USP and Ph.Eur. specifications.

Buyers sourcing for regulated pharmaceutical or personal care applications should confirm compendial compliance. Always verify certificate of analysis documentation with each lot to ensure the highest quality standards.

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Physical Properties

Melting Point111 °C
Boiling Point170°C
Density1.1799
Flash Point167°C
Appearancewhite to light yellow fine powder
ColorWhite to Almost white
FormPowder
Water Solubility92mg/L(25 ºC)
Vapor Pressure0Pa at 25℃
Refractive Index1.5805
Log P2.185 at 25℃

Safety & Handling

Warning GHS07 Hazard Statements H315 H315 H319 H319 H335 H335 Precautionary Statements P261 P261 P264 P264 P271 P271 P280 P280 P319 P319 P321 P321 P405 P405 P501 P501 P264+P265 P264+P265 P302+P352 P302+P352 P304+P340 P304+P340 P332+P317 P332+P317 P337+P317 P337+P317 P362+P364 P362+P364 P403+P233 P403+P233 P305+P351+P338 P305+P351+P338

Trade & Regulatory

HS Code29181990
Storage Class13 - Non Combustible Solids
WGK (Germany)3

Other Names

Phenylmethyl 4-hydroxybenzoate | p-Hydroxybenzoic acid benzyl ester | Benzyl p-hydroxybenzoate | Benzyl parahydroxybenzoate | Benzyl 4-hydroxybenzoate | Benzyl Tegosept | Benzoic acid4-hydroxy-phenylmethyl ester | Benzoic acidp-hydroxy-benzyl ester

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Chemical Properties

CAS Number
94-18-8
EC Number
202-311-9
Mol. Weight
228.24
HS Code
29181990

Industries

Documentation