Overview
3-Pyridinemethanol (CAS 100-55-0 ), also known as nicotinyl alcohol, is a pyridine-based primary alcohol used across pharmaceutical synthesis, flavoring, and specialty chemical manufacturing.
It functions primarily as a reactive intermediate and surface-active agent, enabling downstream production of more complex molecules and formulations in various industrial sectors.
In pharmaceutical manufacturing, it serves as a key building block for synthesizing active ingredients and drug candidates, particularly where a pyridine-containing alcohol moiety is required.
Food and flavor formulators incorporate it as a flavoring agent, where its characteristic profile contributes to specific taste compositions in approved applications for the food industry.
In polymer and resin systems, it acts as a surface modifier and wetting agent, improving adhesion and substrate compatibility in coatings and plastic formulations for industrial use.
Personal care chemists also evaluate it as a stabilizing component in preservation systems where biocidal or antioxidant activity is needed alongside formulation compatibility and stability.
The material is supplied as a liquid at standard commercial purities, typically ranging from 98% to 99%+ for synthesis-grade material to ensure high performance in chemical reactions.
Pharmaceutical-grade material is available to meet the purity and quality documentation requirements of API and intermediate manufacturing for global regulatory compliance.
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Physical Properties
| Melting Point | -6.5 °C |
| Boiling Point | 114 °C @ Press: 12 Torr |
| Density | 1.124 g/mL at 25 °C(lit.) |
| Flash Point | >230 °F |
| Appearance | CLEAR LIGHT YELLOW TO YELLOW LIQUID |
| Color | clear light yellow |
| Form | liquid (clear) |
| Water Solubility | soluble |
| Vapor Pressure | 0.342Pa at 20℃ |
| Refractive Index | n 20/D 1.545(lit.) |
| pH | 7-8 (100g/l, H2O, 20℃) |
| Log P | -0.11 at 25℃ |
Safety & Handling
Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29333999 |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 3 |
Other Names
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Chemical Properties
- CAS Number
- 100-55-0
- EC Number
- 202-864-6
- Mol. Weight
- 109.13
- HS Code
- 29333999
- Category
- Flavors & Fragrances