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Flavors & Fragrances

3-Pyridinemethanol

CAS: 100-55-0

Overview

3-Pyridinemethanol (CAS 100-55-0 ), also known as nicotinyl alcohol, is a pyridine-based primary alcohol used across pharmaceutical synthesis, flavoring, and specialty chemical manufacturing.

It functions primarily as a reactive intermediate and surface-active agent, enabling downstream production of more complex molecules and formulations in various industrial sectors.

In pharmaceutical manufacturing, it serves as a key building block for synthesizing active ingredients and drug candidates, particularly where a pyridine-containing alcohol moiety is required.

Food and flavor formulators incorporate it as a flavoring agent, where its characteristic profile contributes to specific taste compositions in approved applications for the food industry.

In polymer and resin systems, it acts as a surface modifier and wetting agent, improving adhesion and substrate compatibility in coatings and plastic formulations for industrial use.

Personal care chemists also evaluate it as a stabilizing component in preservation systems where biocidal or antioxidant activity is needed alongside formulation compatibility and stability.

The material is supplied as a liquid at standard commercial purities, typically ranging from 98% to 99%+ for synthesis-grade material to ensure high performance in chemical reactions.

Pharmaceutical-grade material is available to meet the purity and quality documentation requirements of API and intermediate manufacturing for global regulatory compliance.

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Physical Properties

Melting Point-6.5 °C
Boiling Point114 °C @ Press: 12 Torr
Density1.124 g/mL at 25 °C(lit.)
Flash Point>230 °F
AppearanceCLEAR LIGHT YELLOW TO YELLOW LIQUID
Colorclear light yellow
Formliquid (clear)
Water Solubilitysoluble
Vapor Pressure0.342Pa at 20℃
Refractive Indexn 20/D 1.545(lit.)
pH7-8 (100g/l, H2O, 20℃)
Log P-0.11 at 25℃

Safety & Handling

Warning GHS07 Hazard Statements H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29333999
Storage Class10 - Combustible liquids
WGK (Germany)3

Other Names

Pyridin-3-ylmethanol | Nicotinyl alcohol

Related Products

Chemical Properties

CAS Number
100-55-0
EC Number
202-864-6
Mol. Weight
109.13
HS Code
29333999

Industries

Documentation