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Chelating Agents

Tetrasodium edetate dihydrate

CAS: 10378-23-1

Overview

Tetrasodium edetate dihydrate (CAS 10378-23-1 ), commercially known as EDTA-4Na, is a fully neutralized sodium salt of EDTA supplied in hydrated form. It functions as a chelating and sequestering agent, binding metal ions such as calcium and magnesium.

By binding iron and copper, it prevents these metal ions from interfering with formulations, processes, or finished products. In personal care and cosmetics, EDTA-4Na stabilizes formulations by deactivating trace metals that would otherwise degrade preservative systems.

This prevents rancidity and ensures long-term product integrity for consumer use. Water treatment operations use it to sequester hardness ions and control scale formation in industrial circuits, improving overall system efficiency and reducing maintenance costs.

Textile and leather processing relies on it to prevent metal-catalyzed oxidation during bleaching and dyeing. This protects color consistency and fabric integrity throughout the manufacturing cycle, ensuring high-quality results for industrial textile producers.

In food-compatible applications, it functions as a sequestrant to maintain product stability and extend shelf life where metal contamination is a processing risk. This makes it a versatile additive for various sensitive manufacturing environments.

Tetrasodium edetate dihydrate is supplied as a white crystalline powder or granules. It is available in technical grade for industrial applications and food-grade specifications meeting FCC and BP standards for high purity requirements.

Packaging ranges from small bags to bulk quantities, with concentration typically expressed on a dihydrate basis. This ensures accurate dosing and handling for large-scale chemical operations and specialized laboratory applications alike.

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Physical Properties

Melting Point>300°C
Flash Point350°C
Appearancewhite crystals or powder
ColorYellow-Orange
FormLiquid
Water Solubilityalmost transparency
pH10.5-11.5 (50g/l, H2O, 20℃)

Safety & Handling

Danger GHS05 GHS07 Hazard Statements H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29224999
WGK (Germany)3

Other Names

EDTA tetrasodium salt dihydrate | Ethylenediaminetetraacetic acid tetrasodium salt dihydrate | Tetrasodium ethylenediaminetetraacetate dihydrate | 3JGX4KKZ4A | Acetic acid(ethylenedinitrilo)tetra-tetrasodium saltdihydrate | EDETIC ACID TETRASODIUM SALT DIHYDRATE | GLYCINENN'-12-ETHANEDIYLBIS(N-(CARBOXYMETHYL)-SODIUM SALTHYDRATE (1:4:2) | GLYCINENN'-12-ETHANEDIYLBIS(N-(CARBOXYMETHYL)-TETRASODIUM SALTDIHYDRATE | EDTA-4Na

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Chemical Properties

CAS Number
10378-23-1
EC Number
600-485-4
Mol. Weight
416.20
HS Code
29224999

Industries

Documentation