Overview
Etidronate disodium (CAS 7414-83-7 ), also known as HEDP disodium, is the disodium salt form of hydroxyethylidene diphosphonic acid used commercially as a chelating and sequestering agent.
It binds metal ions, particularly calcium and heavy metals, to prevent scale formation, oxidative degradation, and microbial activity across industrial and formulated product applications.
In water treatment, it controls calcium carbonate and metal oxide scale in cooling towers, boilers, and process water systems. Personal care formulators incorporate it into shampoos and creams.
It is used in rinse-off products to sequester trace metals that would otherwise destabilize peroxide-based systems or accelerate rancidity. Textile and leather processing operations use it to deactivate hardness ions.
This improves process consistency and color yield in dye baths and bleaching liquors. In pharmaceutical manufacturing, it functions as a stabilizing excipient in liquid formulations where oxidation must be controlled.
Etidronate disodium is supplied as a white crystalline powder and as aqueous solution, with solution concentrations typically around 30–40%. Standard grades include technical and pharmaceutical specifications.
Material is available to meet USP and BP standards, with food-contact and cosmetic-grade material available to meet purity requirements for various regulated applications.
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Physical Properties
| Melting Point | >300 °C |
| Appearance | White Crystalline Solid |
| Color | white |
| Form | solid |
| Water Solubility | Soluble in water (26 mg/ml). |
Safety & Handling
Warning GHS07 Hazard Statements H302 Harmful if swallowed H319 Causes serious eye irritation H413 May cause long lasting harmful effects to aquatic life Precautionary Statements P264 Wash … thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P330 Rinse mouth. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P301+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| HS Code | 29319090 |
| WGK (Germany) | 1 |
Other Names
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Chemical Properties
- CAS Number
- 7414-83-7
- EC Number
- 230-458-3
- Mol. Weight
- 249.99
- HS Code
- 29319090
- Category
- Oxidizers & Peroxides