Overview
Calcium disodium edetate hydrate (CAS 23411-34-9 ) is the hydrated crystalline form of calcium disodium EDTA, a chelating agent used across food and pharmaceutical manufacturing. It works by binding free metal ions that would otherwise catalyze oxidative degradation.
In food processing, it is incorporated into canned vegetables, legumes, mayonnaise, and salad dressings to prevent metal-catalyzed discoloration and rancidity. This extends shelf life without altering the flavor profile of the finished product.
Pharmaceutical formulators use it to stabilize liquid drug products, ophthalmic solutions, and topical preparations where trace metal contamination threatens active ingredient integrity. It ensures the long-term stability of sensitive medicinal compounds.
It also functions as a sequestrant in personal care formulations, preventing soap scum formation and improving preservative efficacy. It achieves this by stripping metal cofactors from microbial cell walls during the preservation process.
Industrial cleaning and water treatment applications rely on it to control scale-forming metal ions in process systems. This prevents the buildup of mineral deposits that can damage equipment or reduce the efficiency of industrial operations.
Calcium disodium edetate hydrate is supplied as a white crystalline powder. It is available in food-grade and pharmaceutical-grade specifications, with the pharmaceutical form commonly meeting USP , BP , and Ph. Eur. standards.
Packaging ranges from laboratory quantities to bulk industrial volumes depending on the grade and supplier. This versatility allows for its use in both small-scale research and large-scale manufacturing environments across various sectors.
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Physical Properties
| Melting Point | >300°C |
| Color | White to Off-White |
| Form | Solid |
| Water Solubility | water: 1.6g/10 mL, clear, colorless to faintly yellow |
| Log P | -0.434 (est) |
Safety & Handling
Warning GHS07 GHS05 Hazard Statements H315 Causes skin irritation H318 Causes serious eye damage H319 Causes serious eye irritation H335 May cause respiratory irritation Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P264 Wash … thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/protective clothing/eye protection/face protection. P317 Get emergency medical help. P319 Get medical advice/attention if you feel unwell. P321 Specific treatment (see … on this label). P405 Store locked up. P501 Dispose of contents/container in accordance with local regulations. P264+P265 Wash … thoroughly after handling. P302+P352 IF ON SKIN: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P332+P317 Get emergency medical help. P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Trade & Regulatory
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Other Names
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Chemical Properties
- CAS Number
- 23411-34-9
- EC Number
- 607-231-1
- Mol. Weight
- 410.30
- Category
- Salts & Minerals